Feline Distemper (or Feline Panleukopenia Virus)

What is Feline Distemper / FPV in Cats?

FPV / Feline Panleukopenia Virus, otherwise known as Feline Distemper, is a highly contagious, life-threatening infectious disease in cats. It mostly affects kittens and unvaccinated cats, and it can be fatal if not appropriately diagnosed and treated. It is closely related to canine parvovirus (often confused as it is not related to the canine distemper virus).

The feline panleukopenia virus infects and kills the rapidly growing and dividing cells in the body, including cells in the bone marrow, intestines, and skin, and in a developing fetus.

The virus suppresses the production of all white blood cells in the bone marrow. These cells are important to the immune system and are used to fight infection. Without them, the cat is vulnerable to spreading the virus.

Infected cells in the intestines eventually lead to diarrhea, decreased appetite and vomiting. Severe dehydration ensues and the safety barrier between the intestines and the rest of the body breaks down, leading to secondary bacterial infections. The virus spreads quickly and is fatal, if left untreated.

Feline distemper virus is found everywhere in the environment; it is strong and can live for years. The virus can survive in the environment it was shed into or be carried on shoes, paws, bedding, bowls, litter boxes, etc. It can survive at freezing temperatures and room temperatures, and it can also survive the use of certain disinfectants, including iodine and alcohol.

The virus enters the body through the nose or mouth; the specific cat’s immune system determines the number of viral particles that enter the body. Usually, the virus invades the bone marrow and intestines within two to seven days of the cat coming into contact with the virus.

Panleukopenia is considered one of the deadliest cat diseases in the unvaccinated cat population. Kittens, cats with depressed immune systems and pregnant cats are at the highest risk to develop severe clinical signs of this disease.

Symptoms of Feline Distemper / FPV

Symptoms of feline distemper can range from mild to severe and may include the following:

• Lethargy

• Depression

• Vomiting

• Diarrhea

• Painful abdomen (when touched or may appear tense and distended without touching)

• Dehydration

• Weight loss

• Rough or unkempt hair coat

• Fever

• Decreased to absent appetite

• Collapse (in severe cases)

• Bruising of the skin or gums (in severe cases)

Kittens infected in the womb during the late stages of pregnancy may develop cerebellar hypoplasia once born, a condition where the virus affects the formation of a part of the brain called the cerebellum. This is the part that coordinates balance and movement.

Affected kittens will have mild to severe intention tremors and a wide-based stance. They may fall frequently or seem uncoordinated. Luckily, this is not considered a painful condition, and these special-need kittens, if kept in safe environments, can live long happy lives.

Causes of Feline Distemper / FPV

Cats become infected with this virus in utero due to their mother becoming infected while pregnant or being exposed to it in their environment. Kittens can also be infected in utero or via breast milk when feeding from their mother.

A cat carrying feline distemper virus will shed viral particles into the environment through feces, urine, saliva and vomit. Infection occurs when susceptible cats are in contact with these secretions.

Luckily, an infected cat only sheds the virus for a day or two, but since the virus is very stable in the environment, it can live for years. That is why it is common for cats to become infected due to their environment.

Diagnosing Feline Distemper / FPV

Feline panleukopenia can look like many other conditions, such as feline leukemia or feline immunodeficiency virus. Any kitten showing signs of fever, vomiting, diarrhea, depression, and a decreased appetite is a feline panleukopenia suspect. A thorough medical history can be helpful with diagnosis, especially if your cat was recently adopted, has been outdoors frequently, is unvaccinated, and/or has been around other cats.

Your veterinarian will likely do bloodwork to help with the diagnosis. Feline panleukopenia is suspected when exposure history is correlated with very low white blood cells and possibly low red blood cells (anemia).

Fecal testing for feline panleukopenia virus can be performed . If the cat received a panleukopenia vaccine 5-12 days prior to testing, this form of test is often falsely positive. Virus isolation (a test to find the virus in different tissue samples), antibody levels and PCR testing are also available to help confirm suspicions of feline panleukopenia.

Treatment of Feline Distemper / FPV

There is no specific treatment for feline panleukopenia. Dehydration is treated with aggressive intravenous fluid therapy while clinical signs of vomiting and diarrhea are treated with prescription medications.

Antibiotic therapy is often instituted to help control any secondary bacterial infections due to low white blood cell counts. However, antibiotics are not used to treat and clear the actual virus. For kittens and cats who appear in shock, or with severe infections, aggressive therapy and nursing care is necessary for resuscitation, using plasma/blood transfusions and anti-coagulant therapies.

Luckily, cats who do receive and respond well to aggressive therapy during the first few days of feline panleukopenia tend to have a good prognosis for a complete recovery. Kittens infected in utero during the early to middle stages of pregnancy typically do not survive. Those infected in the later stages of pregnancy tend to develop cerebellar hypoplasia but can live happy lives with normal survival times, depending on the severity of the neurological signs.

Prognosis decreases for cats with low protein levels, low temperatures, thin body conditions, and/or severely low white blood cells on bloodwork. These extremely ill cats have a poor prognosis and, on average, will pass away within 12-24 hours.

If a cat recovers from feline panleukopenia, there is usually no permanent damage to their organs, and they develop lifelong immunity to the virus.

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Cat Health

Encephalitis: Brain Inflammation in Dogs

Encephalitis in Dogs

The term encephalitis refers to an inflammation of the brain. However, it also may be accompanied by the inflammation of spinal cord (myelitis), and/or the inflammation of the meninges (meningitis), membranes which cover the brain and spinal cord.

German short-haired pointers, Maltese, and Yorkshire terriers are all found to be predisposed to encephalitis.

Symptoms of Encephalitis

Although symptoms may vary depending on the portion of brain affected, they typically appear suddenly and are rapidly progressive. Such symptoms include:

• Fever

• Seizures

• Behavioral changes (e.g., depression)

• Decreased responsiveness

• Head tilt to either side

• Paralysis of face

• Uncoordinated movements or circling

• Unequal size of pupils (anisocoria)

• Smaller sized pinpoint pupils

• Decreased consciousness, which may worsen as disease progresses

Causes of Encephalitis

• Idiopathic (unknown cause)

• Immune-mediated disorders

• Post-vaccination complications

• Viral infections (e.g., canine distemper, rabies, parvovirus)

• Bacterial infections (anaerobic and aerobic)

• Fungal infections (e.g., aspergillosis, histoplasmosis, blastomycosis)

• Parasitic infections (e.g., Rocky Mountain spotted fever, ehrlichiosis)

• Foreign bodies

Diagnosis of Encephalitis

You will need to give your veterinarian a thorough history of your dog’s health, including the onset and nature of the symptoms, and possible incidents that might have precipitated the unusual behaviors or complications. Your veterinarian may then perform a complete physical examination as well as a biochemistry profile, urinalysis, and complete blood count (the results of which will depend on the underlying cause of the encephalitis).

If your dog has an infection, the complete blood count may show an increased number of white blood cells. Viral infections, meanwhile, may decrease the number of lymphocytes, a type of white cells (also known as lymphopenia). And abnormal reduction in platelets (small cells used in blood clotting) is a good indicator of thrombocytopenia.

To confirm lung involvement and related complications, your veterinarian may require chest X-rays, while MRIs and CT-scans are used to evaluate the brain involvement in detail. Your veterinarian may also collect a sample of cerebrospinal fluid (CSF), which is then sent to a laboratory for cultures. This is necessary for definitive diagnosis and to determine the severity of the problem. If culture assays are unsuccessful, a brain tissue sample may be necessary to confirm the diagnosis, but this is an expensive procedure.

Treatment of Encephalitis

Your veterinarian will focus on reducing the severity of the symptoms, such as brain edema and seizures, and halt the progression of the disease. Severe forms of encephalitis require immediate hospitalization and intensive care. For instance, those suspected of having bacterial infections will be given broad spectrum antibiotics, which can reach the brain and spinal cord.

Living and Management

With proper treatment and care, symptoms gradually improve within two to eight weeks; however, the overall prognosis depends on the underlying cause of the condition. For example, in some dogs, symptoms may reappear once treatment is discontinued. In such instances, a second round of treatment (or long-term treatment) may be required to save the dog's life.

Your veterinarian will schedule regular follow-up exams to evaluate the effectiveness of the treatment and the dog's state of health. Your vet may even recommend a new diet for the dog, especially if it is frequently vomiting or severely depressed.

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dog health

Reasons to Walk Your Dog

There are few things dogs love more than a good walk, whether yours is the social type who loves meeting people or the type who loves to sniff absolutely everything! That’s why National Walk Your Dog Week (October 1-7) is the perfect opportunity to get outside with your pup!

We love seeing our dogs happy – is there anything cuter than that butt wiggle they do when they’re excited? Knowing that a quick walk can make a positive impact in their day is the least we can do to try and match the joy they bring us every day. Here are just a few reasons to swap your next 30-minute Instagram photo session with your dog for an active walk around the block.

Reasons to walk your dog during National Walk Your Dog Week and year-round:

Keep them healthy

While getting exercise to stay healthy is so often at the top of our minds for humans, we often forget that pets need the same! In the Association for Pet Obesity Prevention‘s 2017 clinical survey, 56% of dogs were found to be clinically overweight. This can reduce the quality of their life, reduce their life expectancy, and cause a multitude of issues for your dog. National Walk Your Dog Week is a great time to set a goal to get your pup out into the world for a substantial walk, around 30 minutes, at least a few times a week.

Chill them out

Not only is the time that you walk your dog a nice opportunity to let your pet get some fresh air and exercise, but it can also prevent them from getting destructive out of boredom while you’re away. If they’re tired out, odds are they won’t have as much time to ponder chewing up your favorite pair of shoes! In addition, it can help energetic dogs expel some energy, which can in turn make them calmer around other people or animals.

Show them love

Pets respond well to interaction, which is why they tend to follow you around the house, or continuously nudge your hand until you pet them! When you walk your dog, it’s a great chance to give your undivided attention to your dog and let them know that you care for them. It may seem like a small task on a mounting to-do list to you but can be a bright spot in your pet’s day!

Focus their training

If your dog needs a little bit of practice learning to heel, sit, stay, or follow other basic commands, a walk is a great time to get them into some of those good habits. Practice makes perfect, so incorporating walks and practicing these skills into their everyday routine will make them even more successful.

Boost your mood

Not only will taking your dog on regular walks make you a more active person, but it can also improve your health in other ways! Spending time with pets can lower anxiety and blood pressure, which is why therapy dogs are so useful. They ease tension, reduce loneliness, and can improve heart health.

This National Walk Your Dog Week, do yourself – and your dog! – a favor and get in the habit of walking your pet regularly. What is your favorite place to explore with your dog? Let us know in the comments!

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What is rabies? What do I do if my pet is infected?

What is rabies?

Rabies is a deadly disease caused by a virus that attacks the nervous system. The virus is secreted in saliva and is usually transmitted to people and animals by a bite from an infected animal. Less commonly, rabies can be transmitted when saliva from a rabid animal comes in contact with an open cut on the skin or the eyes, nose, or mouth of a person or animal. Once the outward signs of the disease appear, rabies is nearly always fatal.

What animals can get rabies?

Only mammals can get rabies; birds, fish, reptiles and amphibians do not. In the United States, most cases of rabies occur in wild animals—mainly skunks, raccoons, bats, coyotes, and foxes. In recent years, cats have become the most common domestic animal infected with rabies. This is because many cat owners do not vaccinate their cats and cats can be exposed to rabid wildlife, either outdoors or when bats get into the house. Rabies also occurs in dogs and cattle in significant numbers and, while not as common, has been diagnosed in horses, goats, sheep, swine and ferrets.

All mammals are susceptible to rabies.

Vaccination programs and control of stray animals have been effective in preventing rabies in most pets. Approved rabies vaccines are available for cats, dogs, ferrets, horses, cattle and sheep. Licensed oral vaccines are also being used for mass immunization of wildlife, particularly raccoons.

What are the signs of rabies in animals?

Once the rabies virus enters the body, it travels along the nerves to the brain. Animals with rabies may show a variety of signs, including fearfulness, aggression, excessive drooling, difficulty swallowing, staggering, paralysis and seizures. Aggressive behavior is common, but rabid animals may also be uncharacteristically affectionate. Horses and livestock with rabies also may exhibit depression, self-mutilation, or increased sensitivity to light. Rabid wild animals may lose their natural fear of humans, and display unusual behavior; for example, an animal that is usually only seen at night may be seen wandering in the daytime.

Although the most common signs of rabies are behavioral changes and unexplained paralysis, rabies should be considered in all cases of unexplained neurological disease. There is no treatment once the clinical signs of rabies appear.

Rabies infection of an animal can only be confirmed after death, through a microscopic examination of the animal’s brain.

How great is the risk of rabies to humans?

Rabies remains a major concern worldwide, killing around 59,000 people every year. Almost all of these deaths are due to rabies transmitted by dogs in countries where dog vaccination programs are not sufficiently developed to stop the spread of the virus.

Rabies vaccination and animal control programs, along with better treatment for people who have been bitten, have dramatically reduced the number of human cases of rabies in the United States. Most of the relatively few human cases in this country have resulted from exposures to bats; any contact with bats, even if a bite was not noticed, should be reported to your physician. Extremely rare cases have resulted from corneal or organ/tissue transplants from an infected donor. Dogs are still a significant source of rabies in other countries, particularly in Asia and Africa, so travelers should be aware of this risk and seek medical advice about vaccination prior to traveling outside of the United States.

What can I do to help control rabies?

Remember that rabies is entirely preventable through vaccination.

• Have your veterinarian vaccinate your dogs, cats, ferrets, and select horses and livestock. Your veterinarian will advise you on the recommended or required frequency of vaccination in your area.

• Reduce the possibility of exposure to rabies by not letting your pets roam free. Keep cats and ferrets indoors, and supervise dogs when they are outside. Spaying or neutering your pet may decrease roaming tendencies and will prevent them from contributing to the birth of unwanted animals.

• Don’t leave exposed garbage or pet food outside, as it may attract wild or stray animals.

• Wild animals should never be kept as pets. Not only may this be illegal, but wild animals pose a potential rabies threat to caretakers and to others.

• Observe all wild animals from a distance. A rabid wild animal may appear tame but don’t go near it. Teach children NEVER to handle unfamiliar animals—even if they appear friendly.

• If you see a wild animal acting strangely, report it to the city or county animal control department.

• Bat-proof your home and other structures to prevent bats from nesting and having access to people or pets.

What if my pet has bitten someone?

• Urge the victim to see a physician immediately and to follow the physician’s recommendations.

• Check with your veterinarian to determine if your pet’s vaccinations are up-to-date.

• Report the bite to the local health department and animal control authorities. Local regulations may require that your pet is confined and isolated for monitoring for signs of rabies.

• Immediately report any illness or unusual behavior by your pet to the local health department and to your veterinarian.

• Don’t let your pet stray and don’t give your pet away. The animal must be available for observation by public health authorities or a veterinarian.

• After the observation period, have your pet vaccinated for rabies if its vaccination is not current.

What if my pet has been bitten?

• Consult your veterinarian immediately and report the bite to local animal control authorities.

• Even if your dog, cat or ferret has a current vaccination, he/she should be revaccinated immediately, kept under the owner’s control, and observed for a period as specified by state law or local ordinance. Animals with expired vaccinations will need to be evaluated on a case-by-case basis.

• Dogs, cats and ferrets that have never been vaccinated and are exposed to a rabid animal may need to be euthanatized in accordance with regulations or placed in strict isolation for six months.

• Animals other than dogs, cats, and ferrets that are bitten by a rabid or potentially rabid animal may need to be euthanatized immediately.

What if I am bitten?

• Don’t panic, but don’t ignore the bite. Wash the wound thoroughly and vigorously with soap and lots of water for 15 minutes, then treat with a disinfectant such as ethanol or iodine.

• Call your physician immediately and explain how you were bitten. Follow the doctor’s advice. If necessary, your physician will give you the post exposure treatment recommended by the United States Public Health Service and may also treat you for other possible infections that could result from the bite.

• If possible, confine or capture the animal if it can be done safely. Once captured, don’t try to pick up the animal. Call the local animal control authorities to collect it. If the animal cannot be captured, try to memorize its appearance (size, color, etc.) and where it went after biting you.

• If it is a wild animal, only try to capture it if you can do so without getting bitten again. If the animal cannot be contained and must be killed to prevent its escape, do so without damaging the head. The brain will be needed to test for rabies.

• Report the bite to the local health department. Prompt and appropriate treatment after being bitten and before the disease develops can stop the infection and prevent the disease.

Pets and rabies vaccine bait

Bait containing rabies vaccine is commonly used for mass wildlife immunizations. The bait does not pose a health risk to you or your pets, but it is best to leave the bait undisturbed.​

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Camphor poisoning in pets: the trouble with topical pain or arthritis rubs.

Have you ever had a sore spot on an arm or leg and rubbed a patch of Tiger Balm, only to have your pet get affectionate and lick you? Or maybe they lick your hand to get your attention before you've had time to wash your hands? This could be a serious issue, resulting in an immediate call to the Pet Poison Helpline.

Camphor is commonly found in topical pain or arthritis body rubs. Examples of some common trade names containing camphor include Carmex, Tiger Balm, Vicks VapoRub, Campho-Phenique, etc. Camphor is readily absorbed across the skin, and should never be applied to dogs or cats due to risks for poisoning. Clinical signs of camphor poisoning in pets include local skin irritation, nausea, vomiting, diarrhea, depression, seizures (in large amounts), and even rarely, death (from respiratory depression or seizures).

Poisonous to: Cats, Dogs

Level of toxicity: Generally mild to moderate

Common signs to watch for:

• Local skin irritation

• Nausea

• Vomiting

• Diarrhea

• Depression

• Seizures (in large amounts)

• Death (rarely, from respiratory depression or seizures)

Alternate names: topical, Carmex, Tiger Balm, Vicks, VapoRub, Campho-Phenique, Arthritis Rub

If you think your dog or cat were exposed to camphor, call your veterinarian or Pet Poison Helpline immediately for treatment advice.

24/7 ANIMAL POISON CONTROL CENTER
(855) 764-7661

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