Feline Distemper (or Feline Panleukopenia Virus)

What is Feline Distemper / FPV in Cats?

FPV / Feline Panleukopenia Virus, otherwise known as Feline Distemper, is a highly contagious, life-threatening infectious disease in cats. It mostly affects kittens and unvaccinated cats, and it can be fatal if not appropriately diagnosed and treated. It is closely related to canine parvovirus (often confused as it is not related to the canine distemper virus).

The feline panleukopenia virus infects and kills the rapidly growing and dividing cells in the body, including cells in the bone marrow, intestines, and skin, and in a developing fetus.

The virus suppresses the production of all white blood cells in the bone marrow. These cells are important to the immune system and are used to fight infection. Without them, the cat is vulnerable to spreading the virus.

Infected cells in the intestines eventually lead to diarrhea, decreased appetite and vomiting. Severe dehydration ensues and the safety barrier between the intestines and the rest of the body breaks down, leading to secondary bacterial infections. The virus spreads quickly and is fatal, if left untreated.

Feline distemper virus is found everywhere in the environment; it is strong and can live for years. The virus can survive in the environment it was shed into or be carried on shoes, paws, bedding, bowls, litter boxes, etc. It can survive at freezing temperatures and room temperatures, and it can also survive the use of certain disinfectants, including iodine and alcohol.

The virus enters the body through the nose or mouth; the specific cat’s immune system determines the number of viral particles that enter the body. Usually, the virus invades the bone marrow and intestines within two to seven days of the cat coming into contact with the virus.

Panleukopenia is considered one of the deadliest cat diseases in the unvaccinated cat population. Kittens, cats with depressed immune systems and pregnant cats are at the highest risk to develop severe clinical signs of this disease.

Symptoms of Feline Distemper / FPV

Symptoms of feline distemper can range from mild to severe and may include the following:

• Lethargy

• Depression

• Vomiting

• Diarrhea

• Painful abdomen (when touched or may appear tense and distended without touching)

• Dehydration

• Weight loss

• Rough or unkempt hair coat

• Fever

• Decreased to absent appetite

• Collapse (in severe cases)

• Bruising of the skin or gums (in severe cases)

Kittens infected in the womb during the late stages of pregnancy may develop cerebellar hypoplasia once born, a condition where the virus affects the formation of a part of the brain called the cerebellum. This is the part that coordinates balance and movement.

Affected kittens will have mild to severe intention tremors and a wide-based stance. They may fall frequently or seem uncoordinated. Luckily, this is not considered a painful condition, and these special-need kittens, if kept in safe environments, can live long happy lives.

Causes of Feline Distemper / FPV

Cats become infected with this virus in utero due to their mother becoming infected while pregnant or being exposed to it in their environment. Kittens can also be infected in utero or via breast milk when feeding from their mother.

A cat carrying feline distemper virus will shed viral particles into the environment through feces, urine, saliva and vomit. Infection occurs when susceptible cats are in contact with these secretions.

Luckily, an infected cat only sheds the virus for a day or two, but since the virus is very stable in the environment, it can live for years. That is why it is common for cats to become infected due to their environment.

Diagnosing Feline Distemper / FPV

Feline panleukopenia can look like many other conditions, such as feline leukemia or feline immunodeficiency virus. Any kitten showing signs of fever, vomiting, diarrhea, depression, and a decreased appetite is a feline panleukopenia suspect. A thorough medical history can be helpful with diagnosis, especially if your cat was recently adopted, has been outdoors frequently, is unvaccinated, and/or has been around other cats.

Your veterinarian will likely do bloodwork to help with the diagnosis. Feline panleukopenia is suspected when exposure history is correlated with very low white blood cells and possibly low red blood cells (anemia).

Fecal testing for feline panleukopenia virus can be performed . If the cat received a panleukopenia vaccine 5-12 days prior to testing, this form of test is often falsely positive. Virus isolation (a test to find the virus in different tissue samples), antibody levels and PCR testing are also available to help confirm suspicions of feline panleukopenia.

Treatment of Feline Distemper / FPV

There is no specific treatment for feline panleukopenia. Dehydration is treated with aggressive intravenous fluid therapy while clinical signs of vomiting and diarrhea are treated with prescription medications.

Antibiotic therapy is often instituted to help control any secondary bacterial infections due to low white blood cell counts. However, antibiotics are not used to treat and clear the actual virus. For kittens and cats who appear in shock, or with severe infections, aggressive therapy and nursing care is necessary for resuscitation, using plasma/blood transfusions and anti-coagulant therapies.

Luckily, cats who do receive and respond well to aggressive therapy during the first few days of feline panleukopenia tend to have a good prognosis for a complete recovery. Kittens infected in utero during the early to middle stages of pregnancy typically do not survive. Those infected in the later stages of pregnancy tend to develop cerebellar hypoplasia but can live happy lives with normal survival times, depending on the severity of the neurological signs.

Prognosis decreases for cats with low protein levels, low temperatures, thin body conditions, and/or severely low white blood cells on bloodwork. These extremely ill cats have a poor prognosis and, on average, will pass away within 12-24 hours.

If a cat recovers from feline panleukopenia, there is usually no permanent damage to their organs, and they develop lifelong immunity to the virus.

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Cat Health

Get to Know Your Dog’s Digestive System

A healthy digestive system is essential to your dog’s well-being. The digestive system serves many important functions: it takes in food, absorbs nutrients, maintains fluid and electrolyte balance, and gets rid of waste.

It also covers a lot of area. The digestive tract includes the oral cavity (salivary glands, tongue, teeth), esophagus, stomach, small and large intestine, liver, pancreas, rectum, and anus.

The canine digestive system isn’t the most glamorous topic, but understanding how it works puts you in a better position to determine if your dog is sick and needs to be seen by a vet. It can also guide you in making decisions that will enhance their health.

Here are 7 interesting facts about your dog's gastrointestinal tract and health!

1. Dogs Get Heartburn, Too

Dogs can get indigestion and heartburn just like humans.

In the fasted state, stomach acids are very similar in people and dogs. After eating, however, dogs produce more acid than we do.

Our similarities mean that dogs and people benefit from the same antacids. But before giving your dog an over-the-counter antacid, talk to your veterinarian. You will want to be sure you aren’t risking any potential drug interactions or side effects.

Veterinarians can also provide you with important usage guidance for antacids to ensure you are not putting your pet’s health at risk.

But more stomach acid doesn’t translate to letting your dog eat potentially contaminated foods. Dogs are no less sensitive to food poisoning (bacterial contamination) than are people. The practice of feeding raw meat to dogs carries a demonstrated risk of food poisoning.

2. Food Moves Through a Dog's GI Tract Three Times as Fast

Dogs have a small intestine that occupies about 25% of the total gastrointestinal volume, which is consistent with other omnivores, including people. The small intestine of a cat, a true carnivore, occupies only 15%.

On average, food moves through the canine stomach a bit slower than ours, but food movement through the intestines is a little faster. Gastrointestinal transit time is six to eight hours for dogs, while in people it’s between 20 and 30 hours.

3. Dogs Can’t Chew Side to Side

You’ve probably noticed that your dog can’t chew side to side. The dog’s jaw only allows for up and down motion when chewing, whereas people have side-to-side movement that allows more grinding of food.

The difference probably has to do with our historical diets. The wolf-like ancestors of dogs ate mostly meat that could be easily ripped and swallowed, but people also relied on gathering or farming plant material that required more chewing.

4. Most Dogs Can Digest and Absorb Carbs

But modern dogs are considered omnivores, just like we are. They originally ate a carnivorous diet in the wild, but since they have been domesticated, adaptions have been made that allow them to digest and utilize plant-based nutrients.

True carnivores, like cats, have a higher nutritional requirement for taurine, arachidonic acid and certain vitamins, which are available in animal fat and protein sources.

Omnivores don’t have a higher requirement for these and create their own arachidonic acid from vegetable oils. Most normal dogs have no difficulty digesting and absorbing carbohydrates. So, there is no benefit to feeding grain-free diets to normal dogs.

5. Cholesterol Doesn’t Impact a Dog’s Health

Your doctor may advise you to lower your cholesterol level, but you won’t hear the same concerns echoed at the vet’s office. Cholesterol does not have the same effect on your dog’s heart, and their digestive systems are designed to accommodate animal fat.

Dogs also don’t have the same issues with colon cancer, so the idea that eating foods high in soluble fiber or low in saturated or trans-fats will provide any health benefit is really unknown at this point.

Vets say one of the keys to health is keeping your dog at a healthy weight. Obesity is related to exacerbation of many health problems in dogs and is a vet’s number one battle. If it’s any one thing that we can do, it’s talk to our vets about how to curb obesity.

6. Diarrhea and Vomiting May Be Bigger Problems Than You Thought

Gastrointestinal diseases account for about 10% of veterinary visits. Diarrhea is one of the most frequent clinical signs. Abnormal stool may also be a first symptom of a more systemic disease process, such as kidney, liver, and some endocrine disorders.

Vomiting is also a common symptom. An acute bout may resolve itself over a day or two—vets will often recommend a short, 12-hour period of fasting to “rest” the GI tract, followed by a bland diet of chicken and rice. But when the clinical signs continue or are especially severe, testing is often recommended to attempt to find out what may be causing the distress.

Imbalances with other organs, such as the kidneys, can also cause gastrointestinal signs. It is important to see your vet to determine the best treatment for your dog.

7. Your Dog’s Poop Tells a Lot About Their Health

You can learn a lot about your dog’s health by studying her poop (an unpleasant, but necessary task).

There are a variety of causes for abnormal stool. Most episodes of acute onset diarrhea are typically self-limiting within a few days, as dietary indiscretions are a frequent cause.

Parasites, bacteria, and viruses may also cause diarrhea. Depending on the underlying cause, the animal may or may not need appropriate treatment for the infectious agent. If diarrhea persists for several days, and/or there is blood in the stool, the animal should be examined by a veterinarian who can determine the most appropriate course of treatment.

On the other hand, if your dog isn’t pooping and is straining to defecate, they may be constipated, which if prolonged, may cause serious health issues.

One important takeaway is to contact your vet if you notice anything suspicious. Even short episodes of diarrhea or constipation that occur periodically, especially in combination with other signs, like weight loss and loss of appetite, may indicate a more complicated disease process.

Another key point is that you regularly monitor your dog’s poop habits. It is important for the owner to daily monitor how often the animal defecates and the consistency of the stool. There is some variation between animals and also variation from day-to-day, with some animals having consistently softer stools or harder stools than others. But generally, with time, the owners should be able to establish what’s normal for their animal.

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Let's talk about cat poop!

Healthy Poop in Cats

How often should a cat 'go'?

The general rule of thumb is that a cat should poop at least once a day. However, the frequency of your cat's bowel movements is affected by multiple factors including the age (i.e. kittens defecate more often than adults), diet, exercise, and health status (i.e. IBD, hyperthyroidism, parasites, CKD).

Because of this, the exact frequency of the bowel movement will be individual, and you should monitor for its fluctuations instead. If your cat's bowel movements start to differ from the normal frequency for longer than a day or two, it is advisable to pay a visit to the vet and resolve the cause of the change.

What does healthy poop look like?

Healthy cat poop should be deep brown in color (but not too dark nor black) and malleable in consistency (similar to modeling clay; it should be firm enough to leave little to no residue on the ground when picked up, yet pliable and not too hard). Poop should be passed in one piece or a few smaller pieces of somewhat cylindrical shape and segmented appearance. The odor shouldn't be too foul, although this can be variable.

Unhealthy Poop in Cats

The key signs to look out for in your cat's poop are the consistency, shape and color. The stool's consistency is directly influenced by the amount of moisture in it, which gives you an insight into the colonic health. The colon (or the large intestine) reabsorbs the remaining water and other key nutrients from the indigestible material, thus solidifying this material into the firm stool. The consistency of the stool can be descriptively scored to help you recognize if your cat's stool is healthy.

A comprehensive fecal scoring guide was described by Purina. According to Purina's guide, the consistency of the healthy stool can be scored on the scale from 1 to 7. The healthy stool (as described above) is scored with 2, while the stool that is too hard and dry is scored with 1. Scores from 3 to 7 are reserved for moist, mushy or liquid stools.

Hard stool (score 1) is typically a sign of constipation, which can be associated with dehydration, colon obstruction or certain metabolic and neurological conditions. Thus, if you notice that your cat is passing poop that is too hard in consistency, you should pay a visit to the vet and address the issue. The hard poop is passed in smaller, more spherical pellets which leave no residue on the ground, and the passing itself requires more effort.

Soft, mushy or liquid stools (scores 3-7) can be a sign of bacterial infections, intestinal parasites, or food intolerance. If your cat's poop is moist on the surface, thus leaving residue on the ground, but retains the shape and form when picked up, then its consistency can be scored with 3. This poop has little to no visible segmentation, but is not considered to be an alarming sign.

If the poop is so moist that it feels saggy and it loses form when picked up (but does retain a logged shape when passed), then the consistency can be scored with 4. Furthermore, if the stool is passed in a pile rather than the logs, then it is scored with 5. If your cat passes liquid stool with texture but no shape, then the consistency is scored with 6. Liquid stool without any texture nor shape is scored with 7.

Soft or fluid stool (as described by the scores 4-7), accompanied by a more frequent bowel movement, are referred to as diarrhea. While the causes for diarrhea are variable and often multi-factorial, this state is considered to be an important, sign of underlying problems and is a legitimate reason to consult with your vet. Sometimes, diarrhea can be caused by stress (i.e. moving to a new environment or bringing in a new pet), or food allergies and intolerance.

Other times, however, diarrhea can be a symptom of a disease, a bacterial infection, or even intestinal parasites. If your cat is suffering from diarrhea, make sure to closely monitor the frequency on your cat's bowel movement, so you can report it to your veterinarian. Keep an eye on other signs of disease and injury and the changes in your cat's behavior. This will be key for the diagnosis of the underlying cause.

Contact your veterinarian ASAP after spotting the symptoms, especially if diarrhea persists for more than two days and is accompanied by lack of appetite, lethargy, or vomiting. The veterinarian will diagnose the underlying cause and help you design a special recovery diet for your cat until it recovers.

The stool is a direct insight into its colonic health. It can help you recognize if your cat is eating the right diet and drinking enough water or if it's suffering from certain health problems. So, the next time you clean the litter box, make sure to quickly inspect if your cat's poop is healthy! A healthy cat is a happy cat.

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